Del Nido (DN) cardioplegic solution (CPS) has been widely used during pediatric cardiac surgery. However, its use in the field of adult cardiac surgery is not popular yet. We evaluated efficacy of DN cardioplegia in adult cardiac surgical patients.Fifty-three

The del Nido. (dN) cardioplegia solution, the most commonly used cardioplegia, developed with some of the above- mentioned specific focus, is used by a third of

It was subsequently tried in adult cardiac surgery, with good results. Cardioplegia solutions have been used for myocardial protection in cardiac surgery for decades. Different cardioplegic strategies have been evaluated. Del Nido cardioplegia was initially used in pediatric patients and has been expanding into adult cardiac centers over the last decade. Del Nido cardioplegia is routinely used in clinical practice both in paediatric and adult population in high volume centres. It could be a safe, effective and cheap myocardial protection strategy of universal implementation in cardiac surgery.

It has been used for pediatric cardiac surgery in Boston’s Children Hospital since 1994 and, since 2003, it has been successfully used for adult cardiac surgery as well [8]. 2016-12-30 Del Nido vs. Buckberg Cardioplegia in Adult Isolated Valve Surgery Stephanie L Mick, Michael Robich, Catherine Torma, Annmarie Fatula, Patrick Grady, A. Marc Gillinov, Edward Soltesz, Douglas R Johnston, Joseph F Sabik, III Cleveland Clinic, Cleveland, OH. OBJECTIVES: Del Nido cardioplegia is a non-glucose-based solution given as a single dose that provides up to 180 minutes of cardiac quiescence. Matte GS, del Nido PJ. History and use of del Nido cardioplegia solution at Boston Children's Hospital.

Protecting the aged heart during cardiac surgery: use of del Nido cardioplegia provides … Several studies reported the safety and potential benefits of single‐dose Del Nido cardioplegia (DNC) in selected adult cardiac surgery (ACS) procedures. However, studies are scarce on routine use of DNC in more complex procedures and patients with a high risk profile. Mitsutaka Nakao, Kiyozo Morita, Gen Shinohara, Takashi Kunihara, Excellent restoration of left ventricular compliance after prolonged del Nido single-dose cardioplegia in an in vivo piglet model, Seminars in Thoracic and Cardiovascular Surgery, 10.1053/j.semtcvs.2019.08.003, (2019).

Del Nido cardioplegia Del Nido cardioplegia was developed by Pedro Del Nido and his team at the University of Pittsburgh in 1990s. It has been used for pediatric cardiac surgery in Boston’s Children Hospital since 1994 and, since 2003, it has been successfully used for adult cardiac surgery as well [8].

It allows for longer redosing interval with safety profile and mortality comparable to cold blood cardioplegia as exemplified by lower troponin T release when corrected for the time of myocardial ischemia. We conducted a prospective randomized trial to compare del Nido (DN) cardioplegia with conventional cold blood cardioplegia (St Thomas [STH]) in pediatric patients.

“What it boiled down to is that Del Nido, when deployed for long complex cases becomes a clinical dance. You go from a Mechanic to an Artist if you stay true to basic principals, have the patient’s welfare as your primary concern, and you have a strong negotiating relationship with your surgeon. Anything less is a compromise.”

In our study we compared outcomes of del Nido and St. Thomas cardioplegia in adult open cardiac surgeries. Methods: Sixty patients were studied between January 2017 to December 2017. Out of which 30 patients were operated on St. Thomas cardioplegia … Del Nido cardioplegia is routinely used in clinical practice both in paediatric and adult population in high volume centres. It could be a safe, effective and cheap myocardial protection strategy of universal implementation in cardiac surgery. Additional prospective studies are needed to confirm these data. Del Nido cardioplegia Del Nido cardioplegia was developed by Pedro Del Nido and his team at the University of Pittsburgh in 1990s.

2016-12-30 Del Nido vs. Buckberg Cardioplegia in Adult Isolated Valve Surgery Stephanie L Mick, Michael Robich, Catherine Torma, Annmarie Fatula, Patrick Grady, A. Marc Gillinov, Edward Soltesz, Douglas R Johnston, Joseph F Sabik, III Cleveland Clinic, Cleveland, OH. OBJECTIVES: Del Nido cardioplegia is a non-glucose-based solution given as a single dose that provides up to 180 minutes of cardiac quiescence.
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doi: 10.1111/jocs.12360 (J Card Surg 2014;29:445–449) The del Nido cardioplegia was developed by Pedro del Nido and his team at the University of Pittsburgh in 1990s. It was primarily designed for children and it has been used in pediatric cardiac surgery in Boston's Children Hospital since 1994.

There is no national recommendation on cardioplegia solutions supported by evidences from Nepalese studies. Del Nido cardioplegia Del Nido cardioplegia was developed by Pedro Del Nido and his team at the University of Pittsburgh in 1990s.
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Conclusion: Del Nido cardioplegia is safe and can be used efficiently as an alternative to blood cardioplegia in isolated aortic valve replacement surgery. Keywords: Cardioplegic Solutions. Aortic Valve. Cardiopulmonary Bypass. Heart Arrest, Induced. Cardiovascular Agents. Heart Valve Prosthesis. DOI: 10.21470/1678-9741-2020-0063

Download Citation | Use of del Nido Cardioplegia in Adult Cardiac Surgery | Background del Nido cardioplegia was developed to protect pediatric hearts, and similar to pediatric hearts, older adult Objective: The del Nido cardioplegia solution provides a long period of arrest with single dose as compare to St. Thomas cardioplegia solution. In our study we compared outcomes of del Nido and St. Thomas cardioplegia in adult open cardiac surgeries.

Del Nido cardioplegia Del Nido cardioplegia was developed by Pedro Del Nido and his team at the University of Pittsburgh in 1990s. It has been used for pediatric cardiac surgery in Boston’s Children Hospital since 1994 and, since 2003, it has been successfully used for adult cardiac surgery as well [8].

El trato y la organización excelente L'incidenza è di 3 casi/100.000 abitanti all'anno con probabilità di rottura del 2/ 100.000. Il che signiﬁca che in Italia ci sono circa 1800 nuovi casi ogni anno. Protocolos.

We evaluated efficacy of DN cardioplegia in adult cardiac surgical patients.Fifty-three Asanguinous, Del Nido cardioplegia was used for myocardial protection. Warm induction followed by cold infusion prevented any agglutination and eliminated the need for subsequent cardioplegia doses. Following the cross-clamp period, the heart returned to normal sinus rhythm without need for defibrillation. Composition of del Nido and Blood Cardioplegia Solutions. Del Nido solution is composed of mixed blood and Plasma-Lyte A (1:4) (total volume: 1060 mL). Mannitol (3.26 g), potassium chloride (K, 26 mEq), magnesium sulphate (Mg, 2 g), lidocaine (130 mg), and sodium bicarbonate (13 mEq) were added to the del Nido solution.